Description
Product Characteristics:
Gamma-aminobutyric acid (GABA) receptors are pentameric membrane proteins that operate GABA-gated chloride channels and inhibit neurotransmission in the central nervous system. The rho receptor subunits do not exhibit sensitivity to typical GABA receptor modulators such as bicuculline, hexobarbital, and diazepam. While the rho 1 subunit localizes specifically to the retina, rho 2 expresses in all regions of the brain, though levels were still highest in the retina, implying a role for both subunits in visual pathways.
Subcellular location: Cell membrane
Synonyms: GABA receptor Rho 2 subunit, GABAA receptor, GABAA receptor subunit rho-2, GABAC receptor, GABRR 2, Gamma aminobutyric acid receptor rho 2 subunit [Precursor], Gamma-aminobutyric acid GABA A receptor, rho 2, Gamma-aminobutyric acid receptor subunit rho-2, Rho 2 GABA receptor, GBRR2_HUMAN.
Target Information: GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA receptors, which are ligand-gated chloride channels. The protein encoded by this gene is a member of the rho subunit family and is a component of the GABA receptor complex. [provided by RefSeq, Jul 2008]